CorrectQuestion: A biotechnology startup is developing a CRISPR-based gene therapy that targets a monogenic disorder. Which of the following best describes the primary mechanism by which CRISPR-Cas9 induces therapeutic genetic changes?

Wed, 06 May 2026 04:53:56 +0000

CorrectQuestion: Understanding the Primary Mechanism of CRISPR-Cas9 in Gene Therapy Biotechnology startups are revolutionizing medicine with groundbreaking approaches like CRISPR-based gene therapy, especially for monogenic disorders—conditions caused by a single faulty gene. A key question in this rapidly evolving field is: What is the primary mechanism by which CRISPR-Cas9 induces therapeutic genetic changes? ### CRISPR-Cas9’s Core Mechanism: Precision Genome Editing CRISPR-Cas9 functions as a molecular scalpel guided by RNA to precisely edit DNA at specific locations in the genome. Here’s how it works at a fundamental level: